Optos California

Abstract
Confocal Scanning Laser Ophthalmoscopy (cSLO) Platform
Ultra-Widefield Imaging Capabilities:
200° single-capture field of view, imaging approximately 82% of the retina
Image acquisition time: <0.5 seconds per capture
Available in three model configurations with multiple imaging modality options
Imaging Modalities:
optomap Color (RG): Red (633nm) and green (532nm) laser composite imaging
optomap Plus: Red laser monochromatic imaging for enhanced choroidal detail
optomap af: Autofluorescence imaging using blue excitation wavelength
optomap fa: Fluorescein angiography with dynamic video capability
optomap icg: Indocyanine Green angiography for choroidal circulation assessment
Advanced Imaging Technology
Scanning Mechanism: The California employs confocal scanning laser principles with sequential laser raster scanning across the retinal surface. The confocal aperture eliminates scattered light, enhancing image contrast and resolution compared to conventional fundus photography.
Wavelength Specifications:
Red laser: 633nm (optimal for choroidal penetration and RPE detail)
Green laser: 532nm (enhanced retinal vascular and NFL visualization)
Infrared: Near-infrared wavelengths for enhanced media penetration
Resolution Parameters:
Pixel resolution optimized for peripheral retinal pathology detection
Enhanced dynamic range for simultaneous posterior pole and peripheral detail
Non-mydriatic capability with pupil sizes ≥2mm
Clinical Applications in Retinal Pathology
Diabetic Retinopathy Management: The technology is changing management approaches for diabetic retinopathy, age-related macular degeneration, and uveitis. The 200° field allows detection of peripheral ischemia, neovascularization, and retinal breaks that are frequently missed in conventional 30-50° imaging.
Vascular Analysis: The system excels in detecting peripheral retinal vascular abnormalities, including arteriovenous nicking, cotton wool spots, and microaneurysms extending beyond the posterior pole. The red-free equivalent imaging enhances nerve fiber layer assessment.
Angiographic Capabilities: Dynamic fluorescein angiography provides transit timing analysis crucial for ischemic evaluation, while ICG angiography enables choroidal vascular assessment particularly valuable in polypoidal choroidal vasculopathy and central serous chorioretinopathy diagnosis.
Screening Efficiency: The rapid acquisition time and wide field coverage make the California particularly valuable for diabetic retinopathy screening programs, allowing comprehensive retinal assessment without mydriasis in most cases, significantly improving patient throughput and compliance.